George M. Livingston,David B. Thornburgh,Jeffrey Longmore
申请号：
US11413309
公开号：
US08518434B2
申请日:
2006.04.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention provides a spermicidally and virucidally effective, vaginally applicable formulation, having the following approximate composition of essential ingredients: at least one benzalkonium chloride, in an amount from 0.05 to 0-0.2% at least one spermicide selected from the group consisting of nonoxynols in an amount of from 0.05-12%, octoxynol-9 in an amount of from 0.05-4%, and triclosan in an amount from 0.05-2% a biologically acceptable emollient, in an amount from 1-5% hydroxypropyimethyl cellulose, in an amount from 0.1-3% sodium carbomer, in an amount from 0.1-1% de-ionized water, making up the balance. The composition has the attributes of (a) a semi-solid, essentially clear gel consistency and appearance, and (b) the ability to maintain a presence in the human vagina in the presence of mucous secretions therein, in virucidally effective amounts, for at least 24 hours after application thereto.
