INC.;UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION
发明人:
FERNANDEZ-VALLE, CRISTINA
申请号:
EP13761622
公开号:
EP2825210A4
申请日:
2013.03.13
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Disclosed herein are methods of treating a patient at risk of developing or having a neurofibromatosis or a sporadic schwannoma. In exemplary embodiments, the method involves administering to a subject in need an effective amount of a LIMK modulating agent. Also disclosed are compounds newly identified to be inhibitors of Merlin-null Schwann cell proliferation and/or survival.