UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION; INC.
发明人:
Cristina Fernandez-Valle
申请号：
US14385211
公开号：
US20150105441A1
申请日:
2013.03.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed herein are methods of treating a patient at risk of developing or having a neurofibromatosis or a sporadic schwannoma. In exemplary embodiments, the method involves administering to a subject in need an effective amount of a LIMK modulating agent. Also disclosed are compounds newly identified to be inhibitors of Merlin-null Schwann cell proliferation and/or survival.
