University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Rupangi Vasavada,Nagesha Guthalu Kondegowde
申请号：
US13802159
公开号：
US20130251668A1
申请日:
2013.03.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
It is disclosed herein that osteoprotegerin increases human beta cell proliferation and survival. Methods are provided for increasing beta cell proliferation, but contacting a beta cell with an effective amount of osteoprotegrin, a functional fragment, variant or fusion protein thereof. Methods are also provided for treating a human subject with diabetes, comprising administering to the subject a therapeutically effective amount of osteoprotegerin, functional variant or fusion protein thereof.
