COMBINATION THERAPY INCLUDING ISOPHOSPHORAMIDE MUSTARD, ANALOGS, OR SALTS THEREOF

• 收藏
• 分享

专利权人:

Ziopharm Oncology; Inc.

发明人:

Lawrence EINHORN,Jonathan LEWIS,Hagop YOUSSOUFIAN

申请号：

US13753975

公开号：

US20130196000A1

申请日:

2013.01.30

申请国别(地区):

US

年份:

2013

代理人:

摘要：

In one aspect, a method for treating a subject having a hyperproliferative disorder is disclosed, including administering to the subject a composition including: IPM, an IPM analog, or a pharmaceutically acceptable salt thereof in the dosage from about 70 mg/m2/day to about 160 mg/m2/day etoposide in the dosage up to about 100 mg/m2/day and one or more of carboplatin, cisplatin, oxaliplatin, picoplatin, or a combination thereof in the dosage of from AUC 2 mg/mL/min to AUC 7 mg/mL/min wherein the treatment does not result in a dose limiting toxicity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/