The present invention is directed to the use of Trifluoroacetic acid and its physiologically acceptable salts as keratolytic agent to treat skin lesions characterized by the production of excessive skin by the epidermis.本發明係有關於三氟乙酸或其生理上可接受之鹽作為角質溶解劑以治療由表皮產生過量皮膚為其特徵的皮膚病灶之用途。