TORRENS JOVER, Antoni,ORTUNO-MINGARRO, Rosa Mª,PERICAS-CANO, Àlex,FERRER-MALLOFRÈ, Èric,TORRENS JOVER ANTONI,ORTUNO-MINGARRO ROSA Mª,PERICAS-CANO ÀLEX,FERRER-MALLOFRÈ ÈRIC
申请号：
ES14744558
公开号：
ES2692720T3
申请日:
2014.07.29
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A compound of the general Formula (I), or a pharmaceutically acceptable salt, a stereoisomer, an amide, an ester, a carbamate, a carbonate, a ureido, a phosphate or a biohydrolizable solvate thereof: ** Formula ** in that R1 is selected from the group consisting of substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl； R 2 and R 3, identical or different, are selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkylalkyl and substituted or unsubstituted alkenyl； or R2 and R3 together with the bridge nitrogen atom to which a substituted or unsubstituted non-aromatic heterocyclyl are attached, in which the aryl, heteroaryl or heterocyclyl groups can be substituted, independently, in one or more available positions, with one or more suitable groups selected from OR ',>； = O, SR', SOR ', SO2R', OSO2R ', OSO3R', NO2, NHR ', N (R') 2,>； = N-R ', N (R ') COR', N (COR ') 2, N (R') SO2R ', N (R') C (>； = NR ') N (R') R ', N3, CN, halogen, COR', COOR ', OCOR', OCOOR ', OCONHR', OCON (R ') 2, CONHR', WITH (R ') 2, PO (OR') 2, PO (OR ') R', C1-C12 alkyl, C3 cycloalkyl -C10, C2-C12 alkenyl, C2-C12 alkynyl, aryl, heteroaryl and non-aromatic heterocyclic group, in which each of the R 'groups is independently selected from the group consisting of hydrogen, OH, NH2, SH, CN, halogen, COH, CO-alkyl, COOH, C1-C12 alkyl, C3-C10 cycloalkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, heteroaryl and non-aromatic heterocyclic group.Un compuesto de la Fórmula (I) general, o una sal farmacéuticamente aceptable, un estereoisómero, una amida, un éster, un carbamato, un carbonato, un ureido, un fosfato o un solvato biohidrolizable del mismo:**Fórmula** en la que R1 se selecciona del grupo que consiste en arilo sustituido o no sustituido y heteroarilo sustituido o no sustituido； R2 y R3, idénticos o diferentes, se seleccionan del grupo que consiste en hidrógeno, alqu
