ARIKAWA, YASUYOSHI,JONES, BENJAMIN,LAM, BETTY,NIE, ZHE,SMITH, CHRISTOPHER,TAKAHASHI, MASASHI,DONG, QING,FEHER, VICTORIA
申请号:
DK10800835
公开号:
DK2516434T3
申请日:
2010.12.17
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, L 1 , L 2 , R 1 , R 2 , R 3 , and R 4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula I, pharmaceutical compositions containing them, and their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other disorders, diseases, and conditions for which inhibition of SYK is indicated.