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FUZIONISANI HETEROAROMATSKI PIROLIDINONI KAO SYK INHIBITORI
专利权人:
Takeda Pharmaceutical Company Limited
发明人:
ARIKAWA, Yasuyoshi,JONES, Benjamin,LAM, Betty,NIE, Zhe,SMITH, Christopher,TAKAHASHI, Masashi,DONG, Qing,FEHER, Victoria
申请号:
MEP12515
公开号:
ME02186B
申请日:
2010.12.17
申请国别(地区):
ME
年份:
2016
代理人:
摘要:
Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, L 1 , L 2 , R 1 , R 2 , R 3 , and R 4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula I, pharmaceutical compositions containing them, and their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other disorders, diseases, and conditions for which inhibition of SYK is indicated.text
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中国工程科技知识中心
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