COMPOSES INHIBITEURS ET PROCEDES DE TRAITEMENT DU CANCER

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专利权人:

CRITICAL OUTCOME TECHNOLOGIES INC.

发明人:

DANTER, WAYNE R.

申请号：

CA2730890

公开号：

CA2730890C

申请日:

2009.07.17

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

A synergistically effective combination of an anti-cancer agent and athiosemicarbazone therapeutic compound offormula (I), which is an mTOR-Rictor inhibitor, a Serine 473 phosphorylationinhibitor, an AKT2 inhibitor, or a combinationthereof, for use in the treatment of cancer, and methods and uses thereof.Also included are methods and uses of a thiosemicarbazonefor treating a cancer in a mammal in need thereof, characterized by over-expression of RAS, by an EGFR mutation, and/orby over-expression of AKT2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/