The invention provides a minimally invasive surgery simulation training device, which uses at least one perforation on two sides of a main groove body, a tube is penetrated inside one of the main groove body, and the tube is used to simulate a blood vessel, and the tube is An opening simulates a vascular wound, and fluid flows in the tube to simulate blood. In the present invention, the sensing element senses the fluid in the tube, detects the flow of the fluid out of the opening, and pivots the two side plates and at least one operation. The panel is above one of the main grooves, and a plurality of front operation perforations and at least one observation hole on at least one operation panel are used to allow the surgical instrument to extend into the main groove for simulated surgery training.本發明提供一種微創手術模擬訓練裝置,其係利用主槽體之二側各別設置至少一穿孔,一管件穿設於該主槽體之一內側,並利用該管件模擬血管,將該管件設置一開口模擬血管傷口,以流體流動於該管件中,以模擬血液,本發明再以感測元件感測管件中之流體,偵測流體流出開口之流量,再樞接二側板及至少一操作面板於主槽體之一上方,利用至少一操作面板上之複數前操作穿孔及至少一觀測孔使手術器具可伸至主槽體中,進行模擬手術訓練。