MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE CHILDREN'S MEDICAL CENTER CORPORATION
发明人:
VEISEH, OMID,YESILYURT, VOLKAN,VEGAS, ARTURO,DOLOFF, JOSHUA,ANDERSON, DANIEL G.,LANGER, ROBERT S.
申请号:
CA3027200
公开号:
CA3027200A1
申请日:
2017.06.13
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Zwitterionic polymers or biocompatible polymers with improved properties for cell encapsulation, coating of devices, or a combination thereof are described. The biocompatible polymer contains a zwitterionic monomer, a monomer with a reactive side chain, and optionally another hydrophobic monomer or a neutral hydrophilic monomer. The zwitterionic polymers are cross-linked with a cross-linker via covalent bond to form a zwitterionic hydrogel in the presence of cells. Also provided, are methods of making and using the zwitterionic polymers.