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BIOCOMPATIBLE COATINGS AND HYDROGELS FOR REDUCING FOREIGN BODY RESPONSE AND FIBROSIS
专利权人:
Massachusetts Institute of Technology;The Children's Medical Center Corporation
发明人:
Omid Veiseh,Volkan Yesilyurt,Arturo Vegas,Joshua Doloff,Daniel G. Anderson,Robert S. Langer
申请号:
US15621391
公开号:
US20170355799A1
申请日:
2017.06.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Zwitterionic polymers or biocompatible polymers with improved properties for cell encapsulation, coating of devices, or a combination thereof are described. The biocompatible polymer contains a zwitterionic monomer, a monomer with a reactive side chain, and optionally another hydrophobic monomer or a neutral hydrophilic monomer. The zwitterionic polymers are cross-linked with a cross-linker via covalent bond to form a zwitterionic hydrogel in the presence of cells. Also provided, are methods of making and using the zwitterionic polymers.
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