ERBB-3 (HER3)-SELECTIVE COMBINATION THERAPY

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专利权人:

ENZON PHARMACEUTICALS; INC.

发明人:

LIAO, BAISONG,ZHANG, YIXIAN

申请号：

NZ59232609

公开号：

NZ592326A

申请日:

2009.11.05

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

592326 Disclosed is the use of an oligomer capable of inhibiting expression of HER3 and optionally one or more of HER2 and EGFR genes consisting of 10 to 50 contiguous monomers wherein adjacent monomers are covalently linked by a phosphate group or a phosphorothioate group, and a protein kinase inhibitor of EGFR (HER1), in combination for the manufacture of a medicament for the treatment of cancer in a mammal.

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