The present invention provides a pharmaceutical / cancer treatment method comprising a combination of a compound represented by the general formula (1) having Axl inhibitory activity and an EGFR tyrosine kinase inhibitor. The present invention provides an excellent drug / cancer treatment method that has a high effect of suppressing the resistance of an EGFR tyrosine kinase inhibitor in cancer treatment and has few side effects such as weight loss. The following general formula (1):本発明は、Axl阻害活性を有する一般式（１）で示される化合物とEGFRチロシンキナーゼ阻害薬とを組み合わせてなる医薬／がんの治療方法を提供する。本発明は、がん治療におけるEGFRチロシンキナーゼ阻害薬の耐性を抑止する効果が高く、また、体重減少等の副作用が少ない優れた医薬／がんの治療方法を提供する。下記一般式（１）：【化１】
