Hector F. DeLuca,Katarzyna M. Barycka,Lori Plum,Julia Zella,Margaret Clagett-Dame
申请号：
US11974254
公开号：
US08114393B2
申请日:
2007.10.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides improved methods and compositions for therapeutically controlling and/or reducing serum phosphate levels in animals and mammalian patients. The methods comprise administering to the patient an amount of a dendrimer composition effective to prevent absorption of substantial amounts of phosphate from the patients GI tract. In a preferred version, a dose of between 2.5 and 15 grams per day is effective to prevent over 80% of phosphate present in the patients GI tract from being absorbed. The dendrimer composition may comprise a hydrocitrate, hydrochloride, hydrobromide, hydroacetate or hydroanionic form.
