According to one embodiment, a medical image diagnostic apparatus includes processing circuitry. The processing circuitry configured to generate initial restored signal data by applying a first restoration function to input signal data corresponding to medical signal data concerning an object, generate first element-wise product signal data by calculating an element-wise product of the initial restored signal data and reliability data representing a degree of degradation included in the input signal data, and generate restored signal data by applying a second restoration function to at least one of the input signal data and the initial restored signal data and the first element-wise product signal data.