A measuring device for non-invasive determination of at least one physiological parameter includes at least one diagnostic sensor unit to generate measuring signals, and an evaluation unit for processing of measuring signals. The diagnostic sensor unit is integrated into or connectible to the keyboard of a computer or into a mobile device of entertainment or communication technology, with the diagnostic sensor unit including: an optical measuring unit including at least one radiation source for irradiation of the examined body tissue and at least one radiation sensor for detection of the radiation scattered and/or transmitted from the body tissue, and/or an ECG unit for capturing an ECG signal via two or more ECG electrodes, and/or a temperature or heat sensor, and/or a bio-electrical impedance measuring unit.