PROBLEM TO BE SOLVED: To provide a medicine, excellent in safety, having a new action mechanism for suppressing excessive stress response of the central nervous system and having fewer side effects than a publicly-known antidepressant or anti-anxiety drug.SOLUTION: This invention relates to a heterocyclic compound represented by general formula (1) [in the formula, R1 and R2 independently represent hydrogen, etc., R3 represents a low-grade alkynyl group, etc., and R4 represents a phenyl group, etc.], or a salt thereof.COPYRIGHT: (C)2012,JPO&INPIT【課題】中枢神経系の過剰なストレス応答を抑制する新規な作用機序を有し、公知の抗うつ薬や抗不安薬と比較して副作用が少なく、安全性に優れた医薬を提供する。【解決手段】一般式(1)[式中、R1及びR2は、それぞれ、独立して、水素等を示し、R3は、低級アルキニル基等を示し、R4は、フェニル基等で示す。]で表される複素環化合物又はその塩。【選択図】なし