PROBLEM TO BE SOLVED: To provide a novel central nervous system cell protectant, and an agent for the prevention or treatment of central nervous system degenerative disease.SOLUTION: The present invention provides a compound represented by formula (1) or a pharmacologically acceptable salt thereof, or their prodrugs (R1 is H, an alkyl group, an aralkyl group or the like R2 is -OR4 or -NR5R6 R4-R6 independently represent H, an alkyl group, or an aryl group if R5 and R6 are alkyl groups, R5 and R6 may be bound together to form a ring structure).SELECTED DRAWING: Figure 2COPYRIGHT: (C)2017,JPO&INPIT【課題】中枢神経細胞保護剤、及び中枢神経変性疾患の予防又は治療剤の提供。【解決手段】式(1)で表される化合物若しくはその薬理学的に許容される塩、又はそれらのプロドラッグ。(R1はH、アルキル基、アラルキル基等;R2は-OR4又は-NR5R6;R4~R6は各々独立に、H、アルキル基、又はアリール基;R5及びR6がアルキル基である場合、R5とR6とが結合して環構造を形成していてもよい)【選択図】図2