FACTEURS DE CROISSANCE LIBERES LOCALEMENT POUR FAVORISER LA RECUPERATION MOTRICE APRES UN ACCIDENT VASCULAIRE CEREBRAL

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专利权人:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人:

CARMICHAEL, STANLEY T.,CLARKSON, ANDREW N.

申请号：

CA2829006

公开号：

CA2829006A1

申请日:

2012.03.01

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Methods of improving recovery of a mammal after an ischemic event (e.g., stroke) are provided. In various embodiments the methods involve administering a neural growth factor (e.g., BDNF) into the infarct (e.g., stroke) cavity in a biocompatible hydrogel formulation. In certain embodiments the hydrogel comprises a thiolated hyaluronan and a thiolated gelatin with an optional thiolated heparin.

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