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LOCALLY RELEASED GROWTH FACTORS TO MEDIATE MOTOR RECOVERY AFTER STROKE
专利权人:
The Regents of the University of California
发明人:
Stanley T. CARMICHAEL,Andrew N. CLARKSON
申请号:
US15616862
公开号:
US20170340706A1
申请日:
2017.06.07
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Methods of improving recovery of a mammal after an ischemic event (e.g., stroke) are provided. In various embodiments the methods involve administering a neural growth factor (e.g., BDNF) into the infarct (e.g., stroke) cavity in a biocompatible hydrogel formulation. In certain embodiments the hydrogel comprises a thiolated hyaluronan and a thiolated gelatin with an optional thiolated heparin.
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