A surgical access device comprises an elongate surgical access member having a lumen extending through it that is configured to receive a surgical tool, and a flexible sleeve member having a lumen extending through it that is configured to receive the elongate surgical access member. A substantially rigid collar member is disposed adjacent to a proximal end of the flexible sleeve and has a lumen extending through it that is configured to receive the elongate surgical access member. The collar member can be moved relative to the elongate surgical access member to selectively configure the flexible sleeve in a relaxed condition in which the flexible sleeve has a relatively smooth outer surface and a compressed condition in which the flexible sleeve has a plurality of protrusions formed on the outer surface that are configured to create a seal between the outer surface and tissue. The flexible sleeve is normally in the relaxed condition and is configured to receive a compressive force to be configured in the compressed condition.