Guolin Cai;Jerk Vallgarda;Christopher Tegley;Evert Homan;Davi;Meredith Williams;Eric A. Bercot;Martin Henriksson;Christopher H. Fotsch;Randall W. Hungate;Aiwen Li;Lars Johansson;Chester Chenguang Yuan
发明人:
Martin Henriksson,Evert Homan,Lars Johansson,Jerk Vallgarda,Meredith Williams,Eric A. Bercot,Christopher H. Fotsch,Aiwen Li,Guolin Cai,Randall W. Hungate,Chester Chenguang Yuan,Christopher Tegley,Davi
申请号：
US13233699
公开号：
US08686011B2
申请日:
2011.09.15
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to compounds with the formula (I), (II), (III) or (IV):wherein R1, R2, R3, R4, R5, R6, R7, X and Z are as defined herein, and also to pharmaceutical compositions comprising the compounds, as well as methods of use of the compounds for treatment of disorders associated with human 11-β-hydroxysteroid dehydrogenase type 1 enzyme and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme.
