GENETICALLY MODIFIED RAT MODELS FOR SEVERE COMBINED IMMUNODEFICIENCY (SCID)

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专利权人:

发明人:

Eric M. Ostertag,John Stuart Crawford,Joseph Ruiz

申请号：

US15810272

公开号：

US20180295819A1

申请日:

2017.11.13

申请国别(地区):

US

年份:

2018

代理人:

摘要：

This invention relates to the engineering of animal cells, preferably mammalian, more preferably rat, that are deficient due to the disruption of tumor suppressor gene(s) or gene product(s). In another aspect, the invention relates to genetically modified rats, as well as the descendants and ancestors of such animals, which are animal models of human cancer and methods of their use.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/