Drew C. Deniger;Steven A. Rosenberg;Anna Pasetto;Rami Yoseph;Winifred M. Lo;Yong-Chen Lu;Maria R. Parkhurst;Paul F. Robbins;Parisa Malekzadeh
发明人:
Drew C. Deniger,Steven A. Rosenberg,Anna Pasetto,Rami Yoseph,Winifred M. Lo,Yong-Chen Lu,Maria R. Parkhurst,Paul F. Robbins,Parisa Malekzadeh
申请号：
US16651242
公开号：
US20200277352A1
申请日:
2018.09.17
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated human p53. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
