ANALOGUES DE COMPOSE DE TYPE AZOLE ET LEURS METHODES D'UTILISATION

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专利权人:

UNIVERSITY OF CONNECTICUT

发明人:

HADDEN, MATTHEW KYLE

申请号：

CA3073228

公开号：

CA3073228A1

申请日:

2018.08.20

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

Disclosed herein are analogues of itraconazole that are both angiogenesis and hedgehog signaling pathway inhibitors, formulations thereof, including lipsome formulations thereof. The compounds are expected to be useful in the treatment of cell proliferation disorders such as cancer, particularly cancers that are dependent upon the hedgehog signaling pathway such as basal cell carcinoma and medulloblastoma.

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