Provided herein is an oral formulation and suspension of a pharmaceutical composition comprising sonidegib that is useful for treating diseases related to activity of Hedgehog signaling pathway including, for example, cancers of the brain, muscle, skin, and prostate； medulloblastoma； pancreatic adenocarcinomas； and small-cell lung carcinomas.本發明提供一種包含索尼蒂吉伯(sonidegib)之醫藥組合物的口服調配物及懸浮液，其適用於治療與Hedgehog信號傳導路徑之活性相關的疾病，包括例如腦癌、肌肉癌、皮膚癌及前列腺癌；神經管胚細胞瘤；胰臟癌；及小細胞肺癌。
