PROBLEM TO BE SOLVED: To provide a block copolymer that forms micell in water or buffers at the transition temperature or lower and aggregates or undergoes a phase transition at the transition temperature or above by using, as the hydrophobic portion, a depsipeptide structure including temperature-responsive sequences and by using, as the hydrophilic portion, a hydrophilic polymer structure and to provide a composition that has the excellent ability to form micell in aqueous solvents and exhibits a phase transition by heating.SOLUTION: The block copolymer has the portion of a hydrophilic polymer structure and the portion of a depsipeptide structure including temperature-responsive sequences. The composition containing the block copolymer is also provided.COPYRIGHT: (C)2009,JPO&INPIT【課題】疎水部に温度応答性配列を含むデプシペプチド構造を、親水部に親水性高分子構造を用いて、水または緩衝液中にて転移温度以下ではミセルを形成し、転移温度以上では凝集または相転移する、ブロック共重合体を提供し、水系溶媒中での優れたミセル形成能と加温によって相転移を起こす組成物を提供する。【解決手段】親水性高分子構造部分と温度応答性配列を含むデプシペプチド構造部分を有するブロック共重合体、および当該ブロック共重合体を含む組成物。【選択図】なし
