HAN, TAE DONG,TAK, HEE JAE,KIM, EUN KYUNG,CHOI, SU BIN,KIM, DONG HOON,PARK, SOL,JUNG, EUN HYE,CHOI, HYUN HO,KIM, TAE WANG,JU, MI KYEONG,HA, NA RY
申请号:
CA3093051
公开号:
CA3093051A1
申请日:
2019.03.20
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The aryl or heteroaryl triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).