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ACIDIC INSULIN PREPARATIONS WITH IMPROVED STABILITY
专利权人:
SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人:
BRUNNER-SCHWARZ, ANETTE,LILL, NORBERT
申请号:
HRP20041200
公开号:
HRP20041200B1
申请日:
2004.12.17
申请国别(地区):
HR
年份:
2013
代理人:
摘要:
Union of welded metal tubes provided with a lining, resistant to attack by Fluids circulating in its interior.The tubes are machined Inside in the area near the ends together, forming an Undercut at each end is inserted into the annular Space formed by two Hollow destalonamientos a Spacer Ring whose Outer diameter is substantially equal to the ma You destalonamientos,And whose axial length is substantially equal to or less than the sum of the axial extensions of the destalonamientos the tubes together, while the Ring separator formed by an annular outer layer of high thermal conductivity metal layer and at least one Inner Ring D And Heat Resistant and Thermal Insulating material.Hal u00e1ndose annular outer layer in contact with the thermally Conductive metal tubes within the Undercut and being United, the metal tubes by Welding Seam.Izum se odnosi na farmaceutsku formulaciju koja sadrži polipeptid odabran iz skupine koju čine inzulin, inzulinski metabolit, inzulinski analog, inzulinski derivati ili njihove kombinacije, površinski aktivno sredstvo ili kombinaciju od nekoliko površinski aktivnih sredstava, prema potrebi konzervans ili kombinaciju od više konzervansa, i prema potrebi sredstvo za izotonizaciju, pufere ili dodatna pomoćna sredstva ili njihovu kombinaciju. Ova farmaceutska formulacija ima pH vrijednost u kiselom području.
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