James M. Sinambela,Veronika Yuliani,Deasy Diah Dwi R.W.,Raymond R. Tjandrawinata
申请号：
US13882502
公开号：
US20130344181A1
申请日:
2010.11.23
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A pharmaceutical composition comprising a substantially coumarin-free extract derived from cinnamon. Its production method including some steps: grinding the raw material, extracting raw material from previous step by maceration using a first solvent to obtain crude extract of Cinnamomum burmanii, fractionating the extracted raw material from previous step through liquid-liquid extraction using a second solvent, wherein the second solvent is immiscible with the first solvent to obtain substantially coumarin-free extract, and optionally drying the substantially coumarin-free extract.The pharmaceutical composition comprising the substantially coumarin-free extract as a single component or in a combination with suitable pharmaceutical excipient(s) to produce a pharmaceutical composition that is safe to be consumed daily and in long-term use.
