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1- [2-(4-BENZYL-4-HYDROXY-PIPERIDIN-1-YL)-ETHYL]-3-(2-METHYL-QUINOLIN-4-YL)-UREA AS CRYSTALLINE SULFATE SALT
专利权人:
ACTELION PHARMACEUTICALS LTD.
发明人:
REDEY, STEPHANE,史戴芬妮 雷迪,史戴芬妮 雷迪,BUCHMANN, STEPHAN,史帝芬 布屈曼,史帝芬 布屈曼,BONARD, JEAN MICHEL,珍 米雪 伯纳得,珍 米雪 伯納得,WOINET, BERTRAND,伯川德 沃纳特,伯川德 沃納特
申请号:
TW094135555
公开号:
TWI362387B
申请日:
2005.10.12
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
Indeed Dings that Knot is brilliant and non-1- [2- (4- tolyl -4- Hydroxyalkyl bases-piperidin-1-yl)-ethyl] -3- (2- Methyl-quinoline -4- bases)-ureas for inhaling Wet Liu Suan Which are Ji Qi System Prepare methods Shang this Hair Ming Department Off what Chengization Learn Meter Liang. For Jin it, the bright Department Off whats The of this Hair in the Group conjunctions for changing the fixed Knot crystalline substances of the upper Indeed of Learn Meter amounts and 1- [2- (4- tolyl -4- Hydroxyalkyl bases-piperidin-1-yl)-ethyl] -3- (2- Methyl-quinoline -4- bases)-urea Single Independence or With of non-suction Wet sulphur acid Which other compounds purposes. Indeed Dings that Knot is brilliant and non-1- [2- (4- tolyl -4- Hydroxyalkyl bases-piperidin-1-yl)-ethyl] -3- (2- Methyl-quinoline -4- bases)-Niao Tone for inhaling Wet Liu Suan Which are with Wu Yu Medical Drug Group Wu System Prepare Shang , this Hair Ming Department Off what The Chengization Learn Meter Liang for Jin. These sulphur acid Which of the bright also Department Off whats of this Hair are in Tone with the purposes for making As mind The hormone antidotes in object.本發明係關於呈化學計量上確定之結晶及非吸濕性硫酸鹽之1-[2-(4-甲苯基-4-羥基-哌啶-1-基)-乙基]-3-(2-甲基-喹啉-4-基)-脲及其製備方法。進而言之,本發明係關於該呈化學計量上確定之結晶及非吸濕性硫酸鹽之1-[2-(4-甲苯基-4-羥基-哌啶-1-基)-乙基]-3-(2-甲基-喹啉-4-基)-脲單獨或與其他化合物之組合之用途。進而言之,本發明係關於該呈化學計量上確定之結晶及非吸濕性硫酸鹽之1-[2-(4-甲苯基-4-羥基-哌啶-1-基)-乙基]-3-(2-甲基-喹啉-4-基)-脲之調配物於醫藥組物之製備。本發明亦係關於此等硫酸鹽在調配物中作為神經激素拮抗劑之用途。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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