PROCÉDÉS DE RÉPARATION DE DOMMAGE TISSULAIRE À L'AIDE DE MUTANTS RÉSISTANT AUX PROTÉASES DU FACTEUR 1 DÉRIVÉ DE CELLULES STROMALES

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专利权人:

MESOBLAST INTERNATIONAL SÀRL

发明人:

SANDRASAGRA, ANTHONY,WU, WEITAO

申请号：

EP12796309

公开号：

EP2717894A4

申请日:

2012.06.06

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention features methods for treating or ameliorating tissue damage using intravenous administration of compositions that include stromal cell derived factor-1 (SDF-1) peptides or mutant SDF-1 peptides that have been mutated to make them resistant to protease digestion, but which retain chemoattractant activity. Systemic delivery, and specifically intravenous (&ldquo；IV&rdquo；) delivery, of SDF-1 and protease resistant SDF-1 mutants is very effective for the treatment of tissue damage.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/