THORNTON, CHARLES A.,WHEELER, THURMAN,SOBCZAK, KRZYSZTOF,OSBORNE, ROBERT,MILLER, JILL,SWANSON, MAURICE S.
申请号：
CA2664189
公开号：
CA2664189C
申请日:
2007.09.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Disclosed are compositions and methods related to the interaction of polyCUG and polyCCUG repeat RNA and proteins that bind to these repetitive RNA sequences. Also disclosed are methods of treating DM1 or DM2 comprising inhibiting the interaction of poly(CUG)exp or .rho.oly(CCUG)exp RNA with muscleblind proteins, or by causing improvement of spliceopathy in myotonic dystrophy.
