Use of a compound for the manufacture of a medicament for use in therapy of a neurodegenerative condition, wherein the compound is of formula (I): wherein R1 is CHR4&mdashOR5 or CHR4&mdashSR5, or aryl or heteroaryi optionally substituted with one or more groups R6 R2 is alkyl or is part of a ring with R3 R3 is H, alkyl or CH2 (when forming part of a ring with R2) R4 is H or alkyl or is part of a ring with R 5 R5 is aryl or heteroaryi optionally substituted with R7 each R6 is independently alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2alkyl, CONH2, SOMe, SO2NH2, Salkyl, CH2SO2alkyl or OCONalkyl2 R7 is R8 or (CH2)nOR8, R9, CF3, OH, OR9, OCOR9, COR9, COOR9, CONH2, CH2CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHCONHR7, NHCON(R9)2, NHCOR9, NHCOaryl, NHSO2Me, CONH2, SMe, SOMe or SO2NH2 R8 is (CH2)nOR9, (CH)nOR9, (CH2)nCOOR9 or (CH2)nCOaryl R9 is alkyl or cycloalkyl and n is 1 to 4 or a salt thereof.
