PROBLEM TO BE SOLVED: To provide a composition which is effective for ophthalmic diseases associated with hypoxia or ischemia, and to provide an angiogenesis inhibitor composition that suppresses pathologic angiogenesis associated with hypoxia or ischemia.SOLUTION: This invention relates to a composition containing a VAP-1 inhibitor as an active ingredient.【課題】低酸素または虚血に伴う眼疾患に有効な組成物、または、低酸素または虚血に伴う病的な血管新生を抑制する血管新生抑制剤組成物を提供する。【解決手段】VAP-1阻害剤を有効成分として含む組成物。【選択図】なし