Jonathan E. Grob;Holger Sellner;Eric Valeur;Wolfgang Miltz;Aengus Macsweeney;Richard Sedrani;Finton Sirockin;Michael Dechantsreiter;Stefan Andreas Randl
发明人:
Michael Dechantsreiter,Jonathan E. Grob,Aengus Macsweeney,Wolfgang Miltz,Stefan Andreas Randl,Richard Sedrani,Holger Sellner,Finton Sirockin,Eric Valeur
申请号:
US14408216
公开号:
US09452990B2
申请日:
2013.06.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides a compound of formula I a method for manufacturing the compounds of the invention, and its therapeutic uses as inhibitor of the complement alternative pathway and particularly as inhibitor of Factor B for the treatment of e.g. age-related macular degeneration and diabetic retinopathy. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.