LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER
发明人:
REHAN, VIRENDER K.,TORDAY, JOHN S.,WALTHER, FRANS J.,WARING, ALAN J.,GORDON, LARRY M.
申请号：
CA3016810
公开号：
CA3016810A1
申请日:
2017.03.06
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present disclosure provides compositions and therapies that can address both the symptoms and disorders associated with insufficient surfactant production and hyperoxia. In one embodiment, the composition can be formulated for aerosol delivery during ventilation therapy. The composition can comprise one or more of the following: a PPAR gamma agonist, a surfactant peptide, and one or more phospholipids. The compositions are formulated to provide the complementary benefits of reducing the likelihood of developing or the severity of RDS in infants, as well as protecting and promoting lung maturation in a hyperoxic environment.
