A composition and method for enhancing brain development in a pediatric subject, the method including administering to the pediatric subject a nutritional composition having up to about 7 g/100 kcal of a fat or lipid source, wherein the fat or lipid source includes at least about 0.5 mg/100 kcal of milk or non-milk polar lipids； up to about 5 g/100 kcal of a protein source； at least about 15 mg/100 kcal of lactoferrin from a non-human source； about 0.015 g/100 kcal to about 0.15 g/100 kcal of a prebiotic composition including polydextrose and/or galactooligosaccharide； and at least about 5 mg/100 kcal of a source of long chain polyunsaturated fatty acids.用於促進小兒個體之腦部發育的組成物與方法，該方法包含投與營養組成物至該小兒個體，該營養組成物具有最高約7g/100kcal的脂肪或脂質來源，其中該脂肪或脂質來源包含至少約0.5mg/100kcal的乳或非乳極性脂質；最高約5mg/100kcal的蛋白質來源；至少約15mg/100kcal的來自非人類來源之乳鐵蛋白；約0.015g/100kcal至約0.15g/100kcal的益生質組成物，其包含聚葡萄糖及/或半乳寡醣；以及至少約5mg/100kcal的長鏈多不飽和脂肪酸之來源。
