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FOLATE-CONJUGATED MOLECULES FOR DELIVERY OF TOXIC SMALL MOLECULE INHIBITORS TO CANCER CELLS AND METHODS OF USE
专利权人:
Dana-Farber Cancer Institute; Inc.
发明人:
James Bradner,Kimberly Stegmaier,Jun Qi,Anthony Varca,Giovanni Roti
申请号:
US15523518
公开号:
US20180280522A1
申请日:
2015.11.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to novel derivatives of thapsigargin that are chemically modified with a group that targets a cell surface-expressed receptor, and pharmaceutical preparations thereof. The invention further relates to methods of treating diseases such as cancer using the compounds of the invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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