The invention provides compounds having activity as sodium channel (e.g., NaV1.7) inhibitors that are useful for treating sodium channel-mediated diseases or conditions, such as pain, as well as other diseases and conditions associated with the mediation of sodium channels, and compositions containing such compounds and methods for using such compounds and compositions.本發明提供具有作為鈉通道(例如NaV1.7)抑制劑之活性的化合物,其適合用於治療鈉通道介導之疾病或病狀,諸如疼痛,以及其他與鈉通道之介導作用相關之疾病及病狀;及含有此類化合物之組合物以及使用此類化合物及組合物之方法。