A wrist brace comprises (a) a main brace body, (b) an adjustable wrist strap configured to encircle the main brace body about a wearer's wrist, and (c) a lace and rotatable tightening mechanism. The main brace body comprises a semi-rigid splint configured to fit the anterior of a wearer's wrist, extending from the palm to a portion of the anterior of the forearm. The lace and tightening rotatable mechanism is configured to apply tension on the lace thereby tightening the wrist strap about the wearer's wrist and drawing the splint closer to the anterior of the wearer's wrist.