A unilateral chewing monitoring device and a monitoring method, wherein the unilateral chewing monitoring device comprises a first module for detecting a plurality of left potential difference signals generated by chewing during the time period and a second module for detecting a plurality of right potential difference signals generated by the chewing during the time period, and a processing module for obtaining the left potential difference signals and deriving a left potential difference signal average amplitude value, and for obtaining the right potential difference signals and deriving a right potential difference signal average amplitude value. The processing module determines whether it’s unilateral chewing according to the average amplitude value of the left potential difference signal and the average amplitude value of the right potential difference signal. The unilateral chewing monitoring device of the present invention can automatically monitor whether it’s unilateral chewing.本發明提供了單邊咀嚼監測設備及監測方法,其單邊咀嚼監測設備包含:一第一模組,該第一模組檢測一時段內咀嚼行為產生的複數個左側電位差訊號;一第二模組,該第二模組檢測該時段內咀嚼行為產生的複數個右側電位差訊號;以及一處理模組,用於獲取並根據該等左側電位差訊號得到一左側電位差訊號平均幅度值,及獲取並根據該等右側電位差訊號得到一右側電位差訊號平均幅度值,該處理模組至少根據該左側電位差訊號平均幅度值和該右側電位差訊號平均幅度值,判定該時段內是否為單側咀嚼。本發明的單邊咀嚼監測設備可以自動監測是否單側咀嚼。