In ah Kim,Dan Hyo Kim,Jean ny Kwon,Ji Min Park,Young hee Park
申请号：
US15048872
公开号：
US09828605B2
申请日:
2016.02.19
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure relates to a composition for enhancing radiation sensitivity including a PI4K isozyme inhibitor as an active ingredient. As the PI4K isozyme inhibitor, a PI4K isozyme-specific siRNA or antiviral agent according to the present disclosure has an excellent effect of enhancing radiation sensitivity such as reducing viability of the cancer cells and radiation resistance during in radiation irradiation and suppressing and delaying DNA damage repair induced by the radiation by inhibiting the PI4K isozyme to be used as a radiation sensitivity adjuvant and an anticancer treatment assisting agent.
