MODULATION OF TTC39 EXPRESSION TO INCREASE HDL

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专利权人:

Rosanne M. Crooke;Mark Graham;Thomas A. Bell

发明人:

Rosanne M. Crooke,Mark Graham,Thomas A. Bell

申请号：

US13498055

公开号：

US20120270929A1

申请日:

2010.09.24

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Provided herein are methods, compounds, and compositions for reducing expression of a TTC39 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for increasing HDL and/or decreasing PCSK9 in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate cardiovascular disease, or a symptom thereof.

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