PATTERNED DOSING OF IMMUNOSUPPRESSANTS COUPLED TO SYNTHETIC NANOCARRIERS
- 专利权人:
- Petr Ilyinskii;Selecta Biosciences, Inc.
- 发明人:
- Petr Ilyinskii,Takashi Kei Kishimoto
- 申请号:
- US15863076
- 公开号:
- US20180193482A1
- 申请日:
- 2018.01.05
- 申请国别(地区):
- US
- 年份:
- 2018
- 代理人:
- 摘要:
- Provided herein are methods and related compositions for administering viral vectors and synthetic nanocarriers comprising an immunosuppressant. In some embodiments, the methods and compositions provided herein achieve improved transgene expression and/or immune response reduction, such as downregulated IgM and/or IgG immune responses.
- 来源网站:
- 中国工程科技知识中心
相关发明人
相关专利
- BAFF, RELATED BLOCKING AGENTS AND THEIR USE IN STIMULATION AND INHIBITION OF B-CELLS AND IMMUNOGLOBULINS IN IMMUNE RESPONSES
- METHOD OF TREATING HEMORESISTANT TUBERCULOSIS ASSOCIATED WITH HIV INFECTION IN SETTING OF PROFOUND IMMUNOSUPPRESSION
- СПОСІБ ЛІКУВАННЯ ХВОРИХ НА ХІМІОРЕЗИСТЕНТНИЙ ТУБЕРКУЛЬОЗ У СПОЛУЧЕННІ З ВІЛ-ІНФЕКЦІЄЮ НА ТЛІ ГЛИБОКОЇ ІМУНОСУПРЕСІЇ
- TOLERANCE INDUCTION OR IMMUNOSUPPRESSION TO PREVENT IN PARTICULAR GRAFT-VERSUS-HOST-DISEASE (GVHD) BY SHORT-TERM PRE-INCUBATION OF TRANSPLANTED CELL SUSPENSIONS, TISSUES OR ORGANS COATED WITH LIGANDS TO CELL SURFACE MOLECULES
- INDUCTION DE TOLÉRANCE OU IMMUNOSUPPRESSION POUR EMPÊCHER EN PARTICULIER LA RÉACTION DU GREFFON CONTRE L'HÔTE (GVHD) PAR UNE PRÉ-INCUBATION DE COURTE DURÉE DES SUSPENSIONS DE CELLULES TRANSPLANTÉES, TISSUS OU ORGANES REVÊTUS PAR LES LIGANDS SUR LES MOLÉCULES À LA SURFACE DES CELLULES