Peter Crooks;Linda P. Dwoskin;Guangrong Zheng;Sangeetha Sumithran;Davis D. Allen;Zhenfa Zheng;Paul Lockman
发明人:
Peter Crooks,Linda P. Dwoskin,Guangrong Zheng,Sangeetha Sumithran,Davis D. Allen,Zhenfa Zheng,Paul Lockman
申请号:
US12300197
公开号:
US08653275B2
申请日:
2007.05.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.