Peter Crooks,Linda Dwoskin,Guangrong Zheng,Sangeetha Sumithran,David Allen,Zhenfa Zhang,Paul Lockman
申请号:
US14829527
公开号:
US09649301B2
申请日:
2015.08.18
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.