The invention provides a lower limb rehabilitation and activation machine, which drives the sliding component to move back and forth by the driving unit, and drives the supporting component to move continuously, so that the lower limb placed on the supporting component can move back and forth, and then drives the lower limb vein bone marrow, joint and its related nervous system to achieve balanced natural movement, so as to achieve relaxed and healthy activation and rehabilitation.本創作係提供一種下肢復健活化機,藉驅動單元驅動滑動組件作往復運動,帶動支撐組件作連動,使放置於支撐組件上的下肢作往復運動,進而帶動下肢筋脈骨髓、關節及其相關神經系統獲致均衡的自然運動,而達到輕鬆的健康活化復健者。